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Antithrombin III Deficiency (AT III)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Avoid HypovolemiaOptimize HydrationCareful PositioningStroke RiskAnticoagulatedThrombosis Risk

Pathophysiology

Antithrombin is a liver-synthesized serine protease inhibitor that inactivates thrombin, factor Xa, and factor IXa . It supplies up to 80% of the body's inhibition of thrombin generation, and heparin...

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