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Clindamycin (Cleocin)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Classification:
Lincosamide antibiotic, bacterial 50S ribosomal protein synthesis inhibitor
Therapeutic Effects:
Treats anaerobic and gram-positive infections, surgical prophylaxis in beta-lactam-allergic patients, anti-toxin adjunct in toxic shock and necrotizing soft tissue infection, treats community-acquired methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections
Primary Considerations:

Surgical antibiotic prophylaxis - 900 mg IV over 30 min before incision in beta-lactam-allergic patients; redose every 6 hr or after blood loss greater than 1.5 L. Pediatric prophylaxis 10 mg/kg IV...

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