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Desmopressin (DDAVP, Stimate, Minirin)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Classification:
Synthetic vasopressin V2-receptor agonist, antidiuretic, hemostatic agent
Therapeutic Effects:
Antidiuretic for central diabetes insipidus, hemostatic agent in mild hemophilia A and vWD type 1, restores platelet function in uremia, treats nocturnal enuresis
Primary Considerations:

Uremic platelet dysfunction - 0.3 mcg/kg IV over 30 min before invasive procedures restores platelet function within 30–60 min and lasts 6–12 hr. Mild hemophilia A and von Willebrand disease ( vWD )...

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