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DiGeorge Syndrome (DGS)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Difficult AirwayVideo LaryngoscopeAspirationImmunocompromiseSepsisUnstable ElectrolytesOptimize ElectrolytesHyperkalemiaSeizuresArrhythmiasAvoid IV bubblesCyanosisReduced Cardiac OutputPulmonary HypertensionAvoid Pulmonary HypertensionBlood Loss (Excessive)AnemiaHypocalcemiaIrradiated Blood ProductsThrombocytopenia

Pathophysiology

DiGeorge syndrome (DGS) is a microdeletion at 22q11.2, present in about 90% of cases and the most common microdeletion syndrome in humans at roughly 1 in 4,000 to 6,000 live births. Loss of TBX1 and...

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