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Edwards Syndrome (Trisomy 18)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Difficult AirwayVideo LaryngoscopeCareful PositioningFull StomachAspirationHypoxiaAvoid HypoxiaAvoid HypercarbiaAvoid AcidosisPulmonary HypertensionAvoid Pulmonary HypertensionReduced Cardiac OutputAvoid IV bubblesAvoid OpioidsHypothermiaAvoid HypothermiaRenal Dysfunction

Pathophysiology

Edwards syndrome is trisomy of chromosome 18, usually the long arm, and is the second most common autosomal trisomy after trisomy 21 . It occurs in complete, partial and mosaic forms, and its...

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