Goodpasture Syndrome (Anti-GBM Disease)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated July 23, 2026

Renal DysfunctionHyperkalemiaAvoid HypervolemiaHypoxiaAnemiaHypertensionImmunocompromiseUnstable ElectrolytesPulmonary Hemorrhage

Pathophysiology

Goodpasture syndrome is anti-glomerular basement membrane (anti-GBM) disease involving both kidney and lung. Circulating IgG autoantibodies, predominantly IgG-1, target the alpha-3 NC1 domain of type...

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Goodpasture Syndrome (Anti-GBM Disease)

Pathophysiology

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