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Malignant Hyperthermia (MH)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Malignant Hyperthermia RiskAvoid Volatile AnestheticsAvoid SuccinylcholineHyperkalemiaHyperthermiaArrhythmias

Pathophysiology

Malignant hyperthermia ( MH ) is a hereditary skeletal-muscle disorder, most often from an RYR1 mutation, in which exposure to a volatile anesthetic or succinylcholine triggers uncontrolled calcium...

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