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Mannitol (Osmitrol)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Classification:
Osmotic diuretic, sugar alcohol
Therapeutic Effects:
Osmotic diuresis, reduction of intracranial pressure (ICP), reduction of intraocular pressure (IOP), renal tubular flushing
Primary Considerations:

ICP Reduction - Your primary intraoperative use. Draws free water out of brain tissue through osmotic gradient. Works best when the blood-brain barrier is intact. Give as a rapid infusion (15-20 min)...

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