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Myasthenic Crisis

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Skeletal Muscle WeaknessAspirationParalytic SensitivityAvoid SuccinylcholineAvoid OpioidsAvoid Muscarinic AgonistsCopious SecretionsBradycardiaDyspneaDelayed EmergenceAvoid StressorsAvoid Beta BlockersAvoid AminoglycosidesAvoid NeostigminePostoperative Ventilation Likely

Pathophysiology

Myasthenic crisis is an exacerbation of myasthenia gravis ( MG ) in which weakness progresses to respiratory distress and diaphragmatic failure, often requiring prolonged mechanical ventilation. The...

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