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Nalbuphine (Nubain)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Classification:
Mixed opioid agonist-antagonist, kappa agonist / mu antagonist, analgesic
Therapeutic Effects:
Analgesia, opioid-induced pruritus (OIP) relief, partial reversal of opioid side effects while preserving some analgesia
Primary Considerations:

Pruritus Treatment - Best known perioperative use is treating neuraxial opioid-induced pruritus ( OIP ) — particularly after intrathecal or epidural morphine . Low-dose nalbuphine (2.5-5 mg IV)...

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