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Nephrogenic Diabetes Insipidus (NDI)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

HypernatremiaDehydrationHypovolemiaAvoid HypovolemiaAvoid HypotensionAvoid Prolonged FastingOptimize HydrationOptimize ElectrolytesUnstable ElectrolytesHypokalemiaRenal Dysfunction

Pathophysiology

Nephrogenic diabetes insipidus (NDI) is failure of the kidney to respond to antidiuretic hormone ( ADH ). The defect is resistance at the V2 receptor in the collecting tubule, a defective aquaporin-2...

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