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Neuroleptic Malignant Syndrome (NMS)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

HyperthermiaAvoid HyperthermiaArrhythmiasLabile Blood PressureRenal DysfunctionHyperkalemiaUnstable ElectrolytesOptimize ElectrolytesAvoid AcidosisDehydrationOptimize HydrationAutonomic InstabilityAvoid Dopamine AntagonistsRhabdomyolysis

Pathophysiology

Neuroleptic malignant syndrome (NMS) is a life-threatening reaction to dopamine D2 receptor blockade — usually an antipsychotic, but also antiemetics, tricyclic antidepressants and lithium — or to...

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