tablet-yellow

Sodium Bicarbonate

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Classification:
Alkalinizing agent, electrolyte buffer, sodium-channel blocker antidote
Therapeutic Effects:
Alkalinizing buffer, reverses sodium-channel blockade (TCA and local anesthetic toxicity), adjunct for hyperkalemia with acidosis, urinary alkalinization
Primary Considerations:

TCA / sodium-channel blocker overdose - 1–2 mEq/kg IV bolus narrows QRS by overcoming sodium-channel blockade; titrate to QRS less than 100 ms and arterial pH 7.45–7.55 with infusion as needed. Local...

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