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Toxic Epidermal Necrolysis (TEN)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Skin FragilityDifficult AirwayVideo LaryngoscopeCopious SecretionsSepsisShockHypovolemiaDehydrationOptimize HydrationAvoid HypothermiaHypothermiaHypotensionUnstable ElectrolytesAnemiaBlood Loss (Excessive)ImmunocompromiseCareful PositioningRefractory PainDry EyesRenal DysfunctionAvoid AdhesivesLoss of Skin BarrierMucosal Fragility

Pathophysiology

Toxic epidermal necrolysis (TEN), originally Lyell syndrome, is the severe end of the Stevens-Johnson syndrome (SJS)/TEN spectrum — the same drug-induced epidermolysis, divided only by detached body...

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