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Tumor Lysis Syndrome (TLS)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

HyperkalemiaArrhythmiasAvoid SuccinylcholineRenal DysfunctionUnstable ElectrolytesOptimize ElectrolytesOptimize HydrationSeizuresAnemiaDifficult AirwayAvoid Prolonged FastingHyperphosphatemiaHypocalcemia

Pathophysiology

Tumor lysis syndrome (TLS) is the most common oncologic emergency: malignant cells break down en masse and dump their contents into the circulation faster than the kidney can clear them. The result...

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