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Wernicke-Korsakoff Syndrome (WKS)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Delayed EmergenceEmergence DeliriumCareful PositioningOptimize ElectrolytesHypomagnesemiaUnstable ElectrolytesAvoid HyperglycemiaDehydrationOptimize HydrationAspirationWithdrawalAvoid AcidosisEdemaSkeletal Muscle WeaknessFall RiskImpaired Decision-Making CapacityMalnutritionPeripheral Neuropathy

Pathophysiology

Wernicke-Korsakoff syndrome is thiamine (vitamin B1) deficiency injuring the brain. Thiamine pyrophosphate is the cofactor for pyruvate decarboxylation and for transketolase; without it, brain cell...

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